ea0090rc6.1 | Rapid Communications 6: Endocrine-related Cancer | ECE2023
Cristante Justine
, El Sayed Soha Reda
, Denis Josiane
, Ragazzon Bruno
, Constanze Hantel
, Chabre Olivier
, Guyon Laurent
, Cherradi Nadia
Adrenocortical carcinoma (ACC) is a rare malignancy with dismal prognosis. Deregulated microRNA (miRNA) expression has been implicated in ACC aggressiveness. Nevertheless, the mechanisms underlying such deregulations remain unknown. Aberrant Wnt/β-Catenin signaling has been reported in about 40% of ACC and is associated with poor outcome. In the present work, we aimed to investigate the link between constitutive activation of Wnt/β-Catenin pathway and miRNA expressio...